Make your own free website on Tripod.com

Virtual Naval Hospital

Medical Management of Biological Casualties Handbook

Appendix C: Comparative Lethality of Selected Toxins And Chemical Agents in Laboratory Mice

U.S. Army Medical Research Institute of Infectious Diseases,Fort Detrick, Frederick, Maryland
Peer Review Status: Internally Peer Reviewed


AGENT LD50 MOLECULAR SOURCE

(m g/kg) WEIGHT

Botulinum toxin 0.001 150,000 Bacterium

Shiga toxin 0.002 55,000 Bacterium

Tetanus toxin 0.002 150,000 Bacterium

Abrin 0.04 65,000 Plant (Rosary Pea)

Diphtheria toxin 0.10 62,000 Bacterium

Maitotoxin 0.10 3,400 Marine Dinoflagellate

Palytoxin 0.15 2,700 Marine Soft Coral

Ciguatoxin 0.40 1,000 Marine Dinoflagellate

Textilotoxin 0.60 80,000 Elapid Snake

C. perfringens toxins 0.1 - 5.0 35-40,000 Bacterium

Batrachotoxin 2.0 539 Arrow-Poison Frog

Ricin 3.0 64,000 Plant (Castor Bean)

alpha-Conotoxin 5.0 1,500 Cone Snail

Taipoxin 5.0 46,000 Elapid Snake

Tetrodotoxin 8.0 319 Puffer Fish

alpha-Tityustoxin 9.0 8,000 Scorpion

Saxitoxin 10.0 (Inhal 2.0) 299 Marine Dinoflagellate

VX 15.0 267 Chemical Agent

SEB (Rhesus/Aerosol) 27.0 (ED50~pg) 28,494 Bacterium

Anatoxin-A(s) 50.0 500 Blue-Green Algae

Microcystin 50.0 994 Blue-Green Algae

Soman (GD) 64.0 182 Chemical Agent

Sarin (GB) 100.0 140 Chemical Agent

Aconitine 100.0 647 Plant (Monkshood)

T-2 Toxin 1,210.0 466 Fungal Mycotoxin

Next Page | Previous Page | Section Top | Title Page


Virtual Naval Hospital Home | Help | Search | Outline | Disclaimer | Comments
mailto:nlib@vnh.org

All contents copyright 1997-2000 The University of Iowa. All rights reserved.

URL: http://www.vnh.org/